By Dafna D. Gladman (auth.), P. J. Mease MED (RHUUH), P. S. Helliwell DM, PhD, FRCP (eds.)
Atlas of Psoriatic Arthritis
Eds. Mease and Helliwell
A visible advisor to the advanced and inter-related illnesses of psoriatic arthritis and psoriasis, this quantity includes greater than a hundred and fifty photos spanning a large spectrum of diversifications of the disorder. every one bankruptcy includes an introductory assessment, in addition to a chain of appropriate photographs and tables within which the most important info on each one subject is printed. The content material is finished and authoritative, that includes contributions from top specialists who chart the ailments from prognosis via to scientific therapy.
This ebook includes an expansive yet basic to digest precis of the topic, that includes up to date dialogue by way of well known box practitioners at the following areas:
- Aetiology and pathogenesis
- Clinical evaluation
- Paediatric psoriatic arthritis
- Skin disease
- Management of psoriasis
- Treatment of psoriatic arthritis
Along with charting the increase of radiological imaging within the topic, the e-book additionally contains sections on juvenile psoriatic arthritis, with a view to reduction clinicians in distinguishing the features and lines of the ailment in teenagers, in addition to discussions of scientific drug trials.
Overall, the ebook can be of specific curiosity to rheumatologists, dermatologists, and kinfolk practitioners, with the atlas’ pictures specially offering a necessary reference library.
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Additional info for Atlas of Psoriatic Arthritis
It is perhaps more compelling to regard the issue as one of quantity rather than quality – the disease is merely less extensive in PsA rather than a completely different disease process. The radiographic differences can be summarized as: asymmetric sacroiliitis; more frequent non-marginal ‘chunky’ syndesmophytes; less frequent marginal syndesmophytes; paravertebral ossification; and more frequent involvement of cervical spine. The prevalence of spondylitis depends, to some extent, on the method used to identify spinal involvement.
Resnick D NG. Psoriatic arthritis. In: Bone and Joint Imaging. Edited by D Resnick. Philadelphia: WB Saunders, 1989; 320–329. 24. Peng H, Wright V, Usas A et al. Synergistic enhancement of bone formation and healing by stem cell-expressed VEGF and bone morphogenetic protein-4. J Clin Invest 2002; 110:751–759. 25. Austin LM, Ozawa M, Kikuchi T et al. The majority of epidermal T cells in Psoriasis vulgaris lesions can produce type 1 cytokines, interferon-gamma, interleukin-2, and tumor necrosis factor-alpha, deﬁning TC1 (cytotoxic T lymphocyte) and TH1 effector populations: a type 1 differentiation bias is also measured in circulating blood T cells in psoriatic patients.
16. PsA may present in one of several ways. The key features of the classical presentation are summarized in this figure. The main difficulty is differentiation from other common forms of arthritis at presentation. PIP, proximal interphalangeal. 17. Overall, the sex ratio in PsA approximates unity but will vary across the subgroups so that male predominance occurs in the spondylitis predominant form, while females predominate in the most frequent subgroup – symmetrical polyarthritis. Racial differences in the prevalence of psoriasis are reflected in the prevalence of PsA, although precise epidemiology of PsA across ethnic groups is lacking, partly because of a lack of agreed classification criteria.