Xue Er De -Fen Library

Applied Mathematicsematics

Asymmetric Synthesis and Application of α-Amino Acids by Vadim A. Soloshonok and Kunisuke Izawa (Eds.)

By Vadim A. Soloshonok and Kunisuke Izawa (Eds.)

content material: New suggestions of designing micro- and nano encapsulation platforms --
Micro- and nanoencapsulation for foodstuff applications.

Show description

Read or Download Asymmetric Synthesis and Application of α-Amino Acids PDF

Best applied mathematicsematics books

Global Airlines, Third Edition: Competition in a Transnational Industry

Worldwide airways: pageant in a Transnational provides an outline of the altering scene in air shipping overlaying present matters akin to safety, no frills airways, 'open skies' agreements, the end result of the new downturn in fiscal task and the emergence of transnational airways, and takes a ahead having a look view of those demanding situations for the undefined.

Extra info for Asymmetric Synthesis and Application of α-Amino Acids

Sample text

The reagents employed were the aspartate semialdehyde 28, the glycosylated ketoester 29, and the already exploited valuable aminocrotonate 25. This reaction was carried out under M W irradiation and processed using the same orchestrated sequence of polymer supported reagents illustrated in Scheme 7. The target amino ester 30 was isolated in 68% yield. The efficiency of the routes illustrated in Schemes 7 and 8 was validated by preparation of other amino acids so that a collection of eight compounds shown in Figure 3 was obtained in which the elements of diversity were: (i) the galacto and gluco configurations of the pyranose ring, (ii) the a- and P-configurations at the anomeric center, and (iii) the positions of the carbohydrate and amino acid residues in the pyridine ring.

Marshall, G . R. J. Am. Chem. Soc. 1988, 110, 5875-5880. ; Aldhoun, M . , unpublished results. ; Vilarrasa, J. Angew. Chem. Int. Ed. 2007, 46, 3926-3930. Demko, Z. ; Sharpless, K . B . Angew. , Int. Ed. Engl. 2002, 41, 2110-2113. ; Marra, A . Tetrahedron 2007, 63, 6339-6345. Dondoni, A . ; Massi, A . Acc. Chem. Res. 2006, 39, 451-463 and references therein. ; Aldhoun, M . J. Org. Chem. 2007, 72, 7677-7687. C 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. C Chapter 3 Asymmetric Synthesis of Amino Acids with a Tetrasubstituted Carbon Center via Memory of Chirality Takeo Kawabata Institute for Chemical Research, Kyoto University, Uji, Kyoto 611-0011, Japan Asymmetric synthesis of amino acid derivatives with a tetrasubstituted carbon center via memory of chirality is described.

Conclusion Asymmetric intermelucular and intramolecular alkylation of a-amino acid derivatives via memory of chirality has been described. Chiral enaoltes with dynamic axial chirality are responsible for the asymmetric induction.

Download PDF sample

Rated 4.90 of 5 – based on 21 votes